Pharmacology

New PDF release: Challenges in Nonhuman Primate Research in the 21st Century

By Gerhard F. Weinbauer,Friedhelm Vogel

ISBN-10: 3830928394

ISBN-13: 9783830928393

In continuation of the Covance Primate Symposium sequence, the nineteenth Covance Primate Symposium happened in Münster on twenty third & twenty fourth of may well 2012. Altogether, 70 members representing forty three corporations, accumulated for this symposium.
The 2012 Primate Symposium focussed on ?Challenges in Nonhuman Primate examine within the twenty first Century?. The huge participation and the vigorous discussions in the course of the symposium underlined the timeliness and significance of this subject. professional audio system lined 4 significant themes, i.e. biosimilars improvement: regulatory implications, key issues and subsequent steps, optimizing nonhuman primate use in nonclinical security overview, traits in nonhuman primate developmental & reproductive toxicology (DART) and juvenile toxicity review, and relevance and significance of nonhuman primate versions in regulatory toxicology. the advance of biosimilar has taken up velocity significantly and in the meantime has to be thought of a significant component of power drug improvement, but there are nonetheless a few uncertainties und guidance are below improvement. With the elevated specialise in biopharmaceuticals and the linked elevate for utilizing nonhuman primates being the suitable animal version, it turned essential to optimize using this animal version, e.g. refine research designs and animals numbers yet nonetheless execute significant preclinical stories. it seems that major growth has been completed in that context. within the region of nonhuman primate DART and juvenile toxicity evaluate, fresh guide alterations had an incredible impression on species choice, and the experimental layout plus the timing of those stories in the preclinical programmes. ultimately, given the expanding rules and justficiations of utilizing nonhuman primates as experimental versions. it's paramount to appreciate the fundamental and critical position that nonhuman primates can play in drug security review and scientific drug development.

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Challenges in Nonhuman Primate Research in the 21st Century by Gerhard F. Weinbauer,Friedhelm Vogel


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