Pharmacology

Get Blockbuster Drugs: The Rise and Decline of the PDF

By Jie Jack Li

ISBN-10: 0199737681

ISBN-13: 9780199737680

ISBN-10: 1522694366

ISBN-13: 9781522694366

For the world's greatest prescription drug brands, the previous couple of years were a harrowing time. lately, Pfizer's Lipitor, GlaxoSmithKline's Advair, AstraZeneca's Seroquel, and Sanofi-Aventis and Bristol-Myers Squibb's Plavix all got here off patent within the an important U.S. industry. This so-called "patent cliff" intended 1000's of billions of bucks in misplaced profit and has pharmaceutical builders scrambling to create new medications and litigating to increase present patent protections.

Having spent such a lot of his occupation in drug discovery in "big pharma," Dr. Li now gives you an insider's account of the way the drug ascended to its plateau and explores the character of the turmoil it faces within the coming years. He starts with a survey of the panorama ahead of "blockbuster drugs," and proceeds to explain how these medicines have been came across and for this reason turned vital to the enterprise types of huge pharmaceutical businesses. for instance, in early Nineteen Eighties, Tagamet, the 1st "blockbuster drug," remodeled a minor Philadelphia-based drug maker named SmithKline & French into the world's ninth-largest pharmaceutical corporation when it comes to revenues. The venture that introduced Tagamet was once approximately terminated a number of occasions simply because learn efforts started in 1964 produced no obvious effects in the first 11 years. comparable tales accompany the invention and improvement of now-ubiquitous prescribed drugs, between them Claritin, Prilosec, Nexium, Plavix, and Ambien.

These tales, and the features of the pharmaceutical that they show, can educate us worthwhile classes and display many the most important facets concerning the destiny panorama of drug discovery. As constantly, Dr. Li writes in a readable kind and intersperses interesting tales of clinical discovery with enticing human drama.

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Blockbuster Drugs: The Rise and Decline of the Pharmaceutical Industry by Jie Jack Li


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